Most of men experience hair loss, starting from the age of late 20’s and progressing at 50’s. Several factors; such as the frequency of hair wash, skin disorders, infections, malnutrition and medications may lie behind the hair loss in men, but it is mostly secondary to genetic factors.
Testosterone, male hormone, is responsible for hair loss that is secondary to genetic factors. This hormone interacts with 5-Alpha-Reductase enzyme that exists in the capillary bulb and converts into dihydrotestosterone (DHT). DHT leads to thinning and eventually loss of hair. This type of hair loss is called “androgenic alopecia (AGA)”. The up-to-date medical opinion is that many genes play a role in the development of AGA. To date, eight suspected areas on x-chromosome, which include the segment where the androgen gene receptor is coded, are reported. Recent studies claim some interesting genetic links between the early-onset AGA and some other major diseases, but these links have not been proven yet. Besides, it has been proven that increases in Prostaglandin D2 level are also responsible for AGA-type hair loss.
AGA (Androgenic Alopecia) is the most common cause of hair loss among men. Colloquially, the male-pattern hair loss is also known as “ordinary baldness” and “male hair loss”. This type of hair loss develops secondary to the transformation of testosterone, the most active and dominant hormone, into dihydrotestosterone by 5-alpha-reductase enzyme that exists in hair root and the response of hair root to this phenomenon. It generally starts on bilateral temples and is followed by hair loss on vertex and frontal region. In the course of this process, hair gets thinner and weaker. Thick and strong roots turn into babyish thin hair that is hardly noticeable; this phenomenon is called miniaturization. And next, this is followed up by hair loss.
Hair loss and baldness causes a severe stress on individuals and creates negative outcomes that directly affect people’s lives. Patients start losing their self-esteem due to hair loss. Our patients frequently tell our physicians: “I’ve got my self-esteem back.” Androgenic alopecia is seen in half of men who are 50 years old.
This disease is diagnosed with simple tests that are performed in the examination. It is possible to stop or slow down these hair loss problems with proper treatment and procedures.
Norwood Classification is used.